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Chicharros USA - bolsa internacional

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#50331

Re: Chicharros USA - bolsa internacional

Tenía hace mucho tiempo Renta 4, pero era una ruina, así que me cambié a  De Giro. Si ellos no estuvieran probablemente tendría que dejar todo este tema porque yo no voy a largo, voy aqui te pillo aquí te mato..
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#50333

Re: Chicharros USA - bolsa internacional

IMGN

Aparte de la participación prevista en ASCO para el 29 de mayo, la empresa comunica hoy la presentación de resultados preclínicos en relacion a la molécula IMGN151. La presentacion tendrá lugar en el Amercian Association for Cancer Research, entre el 22 y 24 de junio. 

POSTER PRESENTATION 

  • Title: “IMGN151: A Next Generation Folate Receptor Alpha Targeting Antibody Drug Conjugate Active Against Tumors with Low, Medium, and High Receptor Expression” 
  • Day/Time: Monday, June 22, 2020 at 9:00 AM ET 
  • Session Category: Experimental and Molecular Therapeutics 
  • Session Title: Antibody Drug Conjugates 
  • Abstract: 2890 



  •  IMGN151 activity was characterized against cell lines and xenograft models with a wide range of FRα expression and compared to mirvetuximab soravtansine (IMGN853). Cell lines and xenograft models originated from ovarian, endometrial, breast, and cervical cancer. 
  •  In tumor cells with medium and high FRα expression, IMGN151 boosted antibody binding events and payload delivery by 100% and 170%, respectively. 
  •  IMGN151 increased ADC half-life by 60 hours and conjugate exposure in vivo by 40%, as compared to IMGN853. 
  • In vitro, IMGN151 was up to 200 times more active against four FRα-medium cell lines. IMGN151 also had better bystander killing activity in a mixed culture of target-positive and negative cells. 
  • In vivo, IMGN151 induced complete tumor regressions of human tumor xenograft models with high, medium, and low FRα expression. All tested doses were well tolerated. 
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#50335

Re: Chicharros USA - bolsa internacional

APT
yo tb dentro a 16 a ver si da tiron 
Un saludo
1 recomendaciones
#50336

Re: Chicharros USA - bolsa internacional

RMBL

Hoy vuelvo a comprar,  las he estado estudiando y no están nada mal
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